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Pharmalicensing Ltd
is a division of
UTEK Corporation
Companies

Innocoll, Inc.

Innocoll, Inc.
Specialty pharmaceutical and drug delivery company engaged in the research and manufacture of collagen-based technologies for local drug delivery, surgical implants, advanced wound care and oncology.

The company in detail

Profile

Innocoll is an international, specialty pharmaceutical and drug delivery company engaged in the research, development and manufacture of innovative collagen based medical products ulilizing the company's drug delivery technology platforms (CollaRx®and LiquiColl®). These technologies are fully biodegradable and designed for the localized, site-specific delivery of a wide variety of drugs and are specifically intended to minimize systemic exposure and associated side effects.

Localized delivery provides a way of targeting the optimum dose of a drug to precisely where it is needed, rather than distributing excessive and sometimes unnecessary concentrations throughout the body via the systemic circulation. Such delivery systems can enhance a drug's efficacy and reduce unwanted side effects compared to oral or intravenous administration, particularly when targeting poorly vascularized areas such as bone and chronically infected wounds. Localized delivery can also be used as an adjunct to systemic therapy, such as in the prevention of infection or management of pain.

The parent company, Innocoll Inc., has three operating divisions:

• Drug Delivery and R&D Division (Innocoll Technologies)

• Sales and Marketing Division (Innocoll Pharmaceuticals)

• Commercial Manufacturing Division (Syntacoll)

Innocoll Technologies is responsible for the development of new products based upon the proprietary CollaRx and Liquicoll technologies as well as research into new collagen-based pharmaceutical products and medical devices. Internal programs are focussed on treatment and prevention of surgical site infections, advanced wound care, post-operative pain management, prevention of surgical adhesions and oncology. We are also seeking co-development partnerships with pharmaceutical and biotechnology companies interested in using our technologies to develop first-line products or localized delivery line extensions of existing brands.

Innocoll Pharmaceuticals is responsible for establishing and overseeing collabrations with Innocoll's marketing partners. The lead marketed product, Gentamicin Surgical Implant (Collatamp G), is a leave-behind surgical implant indicated for the treatment and prevention of post operative infections. The product is promoted to surgeons across a broad range of surgical specialities, including orthopedic, thoracic, abdominal, and vascular procedures, where there is often increased risk of post-operative infection or where such infections can lead to severe complications. It is currently marketed in more than 30 territories under various trade names throughout most of Europe and other "rest-of-world" countries in Latin America, Middle East, Asia and Africa. Innocoll is also developing Collatamp G for the US market where it is currently in Phase 3 clinical trials for the prevention of surgical site infections and Phase 2 trials as a topical treatment for infected diabetic foot ulcers.

Syntacoll AG (Switzerland) is the holding company for Innocoll's two commercial manufacturing facilities, Syntacoll GmbH in Saal, Germany, and Syntacoll Pty in Midrand, South Africa. An additional manufacturing facility is planned at Innocoll Technologies HQ in Roscommon, Ireland.

Partnering strategy/interests

Out-license of internal pipeline products for the prevention of surgical site infections, treatment and prevention of infected diabetic foot ulcers, advanced wound care, prevention of surgical adhesions and oncology. Partnerships with pharmaceutical and biotechnology companies interested in localized drug delivery of their proprietary molecules.

Out-licensing

Indicated for the treatment and prevention of diabetic foot ulcers. More
Surgical implant for treatment and prevention of post-operative infections More
Gene targeting and localized delivery of anti-neoplastic agents More
Collagen-based adhesion barrier for the prevention of surgical adhesions More
Collagen-based dressings for wound management More
Collagen-based biodegradable matrices for localized drug delivery More

R&D

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Partnerships

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Deals

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Press Releases

(17th Nov 2008) Innocoll Receives Fast Track Designation for Gentamicin Surgical Implant More
(25th Aug 2008) BAXTER ANNOUNCES LICENSING AGREEMENT FOR INNOCOLL’S GENTAMICIN SURGICAL IMPLANT IN THE UNITED STATES More
(8th Aug 2008) Innocoll Announces Dosing of Last Patient in US Phase 2 Clinical Trial to Investigate CollaRx® BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain More
(28th Jul 2008) Innocoll Announces Dosing of First Patient in a Third US Phase 2 Clinical Trial to Investigate CollaRx® BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain More
(21st Jul 2008) Innocoll Appoints Anthony H. Wild Ph.D. to Its Board of Directors More
(30th Apr 2008) Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx® GENTAMICIN TOPICAL for the Prevention of Diabetic Foot Infections More
(17th Apr 2008) Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx® GENTAMICIN TOPICAL for the Treatment of Moderately Infected Diabetic Foot Ulcers More
(13th Mar 2008) Innocoll Announces Dosing of First Patient in a Second US Phase 2 Clinical Trial to Investigate CollaRx® BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain More
(19th Feb 2008) Innocoll Announces Dosing of First Patient in Second US Phase 3 Clinical Trial to Investigate CollaRx® GENTAMICIN SURGICAL IMPLANT for the Prevention of Surgical Site Infections More
(4th Jan 2008) Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx® BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain More
(2nd Jan 2008) Innocoll Announces Dosing of First Patient in US Phase 3 Clinical Trial to Investigate CollaRx® GENTAMICIN SURGICAL IMPLANT for the Prevention of Surgical Site Infections in Cardiac Surgery Patients More
(18th Dec 2007) Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx® GENTAMICIN TOPICAL for the Treatment of Mildly Infected Diabetic Foot Ulcers More
(17th Dec 2007) Innocoll Announces Closing of $30 Million Equity Financing Investment More
(28th Nov 2007) Innocoll Receives "Intends to Grant" Notices from the European Patent Office for Two European Patent Applications Related to Novel Wound Healing, Biosurgery and Drug Delivery Applications of its CollaRx® Technology More
(17th Oct 2007) Innocoll Files Investigational New Drug Application for its CollaRx® BUPIVACAINE TOPICAL for the Treatment of Painful Chronic Skin Ulcers and Burns More
(26th Sep 2007) Innocoll Provides a Progress Update on its Clinical Development Programs and Specialty Pharmaceutical Operations More
(12th Sep 2007) INNOCOLL ENTERS INTO COLLABORATION WITH TGR BIOSCIENCES FOR DEVELOPMENT OF A NOVEL WOUND HEALING PRODUCT More
(10th Sep 2007) Innocoll, Inc. and Bourne Partners Announce Joint Venture to Build Leading U.S. Advanced Wound Care Business - Formation of CollMED Laboratories, Inc. More
(6th Sep 2007) Innocoll Agrees the Sale of its CollaRx® GENTAMICIN SURGICAL IMPLANT and European Sales and Marketing Infrastructure to EUSA Pharma More
(8th Aug 2007) Health Canada Approves Innocoll's CollaRx® GENTAMICIN SURGICAL IMPLANT More
(6th Jun 2007) Innocoll Announces Filing of Investigational New Drug Application for its CollaRx® GENTAMICIN SURGICAL IMPLANT for the Prevention of Surgical Site Infections More
(24th Apr 2007) Innocoll Announces Outcome of FDA Meeting to Commence Phase 3 Development of its CollaRx® GENTAMICIN SURGICAL IMPLANT for the Prevention of Surgical Site Infections More
(11th Apr 2007) Innocoll Files CollaRx® GENTAMICIN SURGICAL IMPLANT in Australia More
(4th Apr 2007) Innocoll Receives FDA Approval to Commence Phase 2 Clinical Development with its CollaRx® BUPIVACAINE IMPLANT for the Management of Post-operative Pain More
(29th Mar 2007) Innocoll Files US and Irish Patent Applications for its CollaRx® BUPIVACAINE IMPLANT for the Management of Post-operative Pain More
(23rd Mar 2007) Innocoll Files CollaRx® GENTAMICIN SURGICAL IMPLANT in Canada and Receives Canadian Medical Devices Conformity Assessment System (CMDCAS) Certification More
(1st Mar 2007) Innocoll Announces Filing of Investigational New Drug Application for its CollaRx® BUPIVACAINE IMPLANT for the Management of Post-operative Pain More
(5th Feb 2007) Innocoll Receives BfArM Approval for a New Version of its CollaRx® Gentamicin Surgical Implant in Germany More
(22nd Jan 2007) Innocoll Receives FDA Approval to Commence a Phase 2 Clinical Trial for the Topical Treatment of Infected Diabetic Foot Ulcers with its CollaRx® GENTAMICIN More
(17th Jan 2007) Innocoll Announces Expansion of the Distribution Partnership for its CollaRx® GENTAMICIN SURGICAL IMPLANT with BurnsAdler to Include Brazil , Dominican Republic and Mexico More
(9th Nov 2006) Innocoll Announces Investigational New Drug Application Filing for its CollaRx Gentamicin as a Topical Treatment for Infected Diabetic Foot Ulcers More
(12th Oct 2006) Innocoll, Inc. announced that its wholly-owned subsidiary, Innocoll Pharmaceuticals, has received US 510k approval for CollaGUARD™, an advanced wound care product based on Innocoll's proprietary CollaRx™ membrane technology. More
(1st Aug 2006) Innocoll Announces a Distribution Partnership for Central and South America and the Caribbean for its CollaRx™ GENTAMICIN SURGICAL IMPLANT More
(26th Apr 2006) Innocoll, Inc. announced its sales and marketing subsidiary, Innocoll Pharmaceuticals Ltd., has launched a new version of its CollaRx Gentamicin Surgical Implant that is specially designed for maximum convenience and ease of use in cardiac surgery. More
(4th Apr 2006) Innocoll, Inc. announced it has recently signed distribution arrangements for its CollaRx GENTAMICIN SURGICAL IMPLANT in Iraq, Iran, Syria, Kazakhstan, Azerbaijan, Georgia, Uzbekistan, Tajikistan and Turkmenistan. More
(30th Mar 2006) Innocoll, Inc. announced its sales and marketing subsidiary, Innocoll Pharmaceuticals Ltd., has recently signed a distribution agreement for its CollaRx GENTAMICIN SURGICAL IMPLANT in the Russian Federation. More
(28th Mar 2006) Innocoll, Inc. announced today that its Drug Delivery Division, Innocoll Technologies Ltd., has initiated a Phase IIA clinical study on the Bupivacaine collagen sponge under development for the management of post-operative pain following moderate/maj More
(7th Mar 2006) Innocoll, Inc. announced its sales and marketing subsidiary, Innocoll Pharmaceuticals Ltd., has obtained approval to promote its GENTAMICIN SURGICAL IMPLANT in Norway. More
(2nd Feb 2006) Innocoll, Inc. announced its sales and marketing subsidiary, Innocoll Pharmaceuticals Ltd., has recently signed two additional distribution agreements for its CollaRx GENTAMICIN SURGICAL IMPLANT in Yemen and Jordan. More
(27th Jan 2006) Innocoll, Inc. announced its sales and marketing subsidiary, Innocoll Pharmaceuticals Ltd., has recently signed a distribution agreement for its CollaRx GENTAMICIN SURGICAL IMPLANT in Hong Kong with Greyon Healthcare Company Ltd. More
(20th Dec 2005) Innocoll, Inc. announced that its wholly-owned subsidiary, Innocoll Pharmaceuticals, has filed a US 510k application for CollaGUARD™, an advanced wound care product based on Innocoll's proprietary CollaRx™ membrane technology. More
(12th Dec 2005) Innocoll, Inc. announced it's sales and marketing subsidiary, has recently signed distribution agreements for it's CollaRx GENTAMICIN SURGICAL IMPLANT in five additional territories; Turkey, Greece, Romania, Bulgaria, Bulgaria, and Nigeria. More
(8th Sep 2005) Innocoll, Inc. announced that its subsidiary, Innocoll Technologies, entered into an agreement with Medexis SA for development of a wound healing product. More
(28th Jul 2005) Innocoll, Inc. announced that its subsidiary, Innocoll Technologies, has entered into a development and distribution agreement with Surgical-IOC for the development of an adhesion barrier product based on Innocoll's CollaRx™ technology. More
(14th Jul 2005) Innocoll, Inc. announced it has recently signed an agreement with Essex Chemie AG, an affiliated company of Schering-Plough Corporation (NYSE: SGP), under which it will obtain marketing rights to GENTAMICIN SURGICAL IMPLANT. More

Senior management

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Board of directors

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Head office

Innocoll, Inc.
Midland Innovations Centre
Dublin Road
Athlone
Co. Westmeath
Ireland

Tel:  +353 90 6486834
Fax: +353 90 6486805
www | email

Contact details

Ms Veronica Kelly
Marketing Executive
Innocoll Pharmaceuticals
Request more information
Mr David Prior
EVP Clinical, Regulatory and Scientific
Innocoll Technologies
Request more information

Company figures

Formed: 2004
Number of employees: 130

Regional and subsidiary offices

Innocoll Technologies Ltd
IDA Business & Technology Park
Castlerea Road
Gallowstown
Co. Roscommon
Ireland

Tel:  +353 906 634902
Fax: +353 906 634895
www | email

Related categories

Industry sector
Animal health / Medical device
Animal health / Pharmaceutical
Biotechnology / Gene therapy
Drug delivery / Parenteral
Drug delivery / Topical
Drug delivery / Parenteral / Implant
Drug delivery / Parenteral / Sustained release
Drug delivery / Topical / Dermatological
Drug discovery / Bioinformatics
Medical device / Therapeutic device
Medical device / Therapeutic medical equipment / Surgical products
Pharmaceutical / Prescription
Pharmaceutical / OTC/Non-Prescription
Pharmaceutical / Generics
Therapeutic target
Accident and Trauma / Bone fractures
Accident and Trauma / Burns
Accident and Trauma / Hemorraghic trauma
Accident and Trauma / Tissue grafting
Accident and Trauma / Wound closure/surgical adhesive
Accident and Trauma / Wound/ulcer healing
Cardiovascular / Treatments / Cardiovascular surgery
Cardiovascular / Cardiovascular disorder (other) / Diabetic cardiovascular disease
Central Nervous System / Pain / Pain, back upper/lower
Central Nervous System / Pain / Pain, chronic
Central Nervous System / Pain / Pain, inflammatory
Central Nervous System / Pain / Anesthesia
Central Nervous System / Pain / Pain management general
Dermatological
Dermatological / Burns
Dermatological / Ulcer, diabetic
Dermatological / Wound healing
Hospital and Surgery / Adhesion
Hospital and Surgery / Anesthesia
Hospital and Surgery / Bleeding
Hospital and Surgery / Infection control
Hospital and Surgery / Surgery (other)
Hospital and Surgery / Tissue grafting
Hospital and Surgery / Wound closure
Metabolism / Diabetic complications
Musculoskeletal / Trauma, physical
Musculoskeletal / Skeletal / Bone repair/regeneration
Oncology / Bone cancer
Oncology / Brain cancer
Oncology / Breast cancer
Oncology / Colorectal cancer
Oncology / Colorectal cancer
Oncology / Colorectal cancer
Oncology / Ovarian cancer
Oncology / Prostate cancer
Oncology / Bladder cancer
Oncology / Cancer side effects / Metastasis
Oncology / Colorectal cancer / Rectal cancer
Oncology / Treatments / Chemotherapy
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