Efficient separation and size sorting of particles by ultrasound waves.
Applications of ultrasound (US) standing waves for separation of particles from a solvent or of biomass from a serum in blood are well known. The advantages of using US separation instead of, e.g., centrifugal one are the possibility to use it in-line and for small volumes, and the simplicity of the control. However, separation by US suffers from complicated removal of the separated phase from the liquid, and does not have the possibility of size sorting of particles. The current technology uses ultrasonic waves of varying wavelengths to enable a continuous process of size separation or particle removal from solutions or biomass.
The outlined technology presents a soft lithography micro-channel device for separation and sorting of particles from a fluid using US. Separation is carried out in a flow to maintain a continuous process of removing separated substances from the complex fluid along the flow.