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Novel Antifungal and Antimicrobial Lipopeptides
Yeda R&D Co. Ltd Israel flag Israel
Abstract ID:
Innovative antimicrobial drugs.The market size for antimicrobial agents is now greater than $25 billion per year. However, the global emergence of resistance to antimicrobial agents is increasingly limiting the effectiveness of current drugs. Novel......
Contact Galit Mazooz, ph.d.
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Innovative antimicrobial drugs.
The market size for antimicrobial agents is now greater than $25 billion per year. However, the global emergence of resistance to antimicrobial agents is increasingly limiting the effectiveness of current drugs. Novel therapeutic approaches that can overcome multidrug-resistant bacteria are therefore in great demand. The present technology utilizes novel lipopeptides with new mode of action that exhibit potent anti-fungal and anti-bacterial activities against a broad spectrum of drug-resistant strains


Applications


• Therapeutics.
• Disinfectants.
• Food preservatives.


Advantages


• Broad range of antibacterial and anti fungal activity, also effective against resistant strains.
• A unique mode of action that reduces the likelihood of developing resistant strains.
• The structure of the molecules allows high versatility that may create a broad range of molecules with unique properties.
• A simple and low cost production process.
• Long shelf life.


Technology's Essence


Naturally occurring antimicrobial peptides, which are part of the innate immunity of all organisms, have the ability to disrupt the microorganism's membrane thereby inducing cell lysis. This effective mode of action reduces the probability for new resistant strains to emerge. The present invention relates to a novel family of potent antimicrobial peptides with unique structural properties that can be utilized to address particular therapeutic needs.


Licensing Status

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FEATURED
Last Updated May 2016
Technology Type THERAPEUTIC
Phase of Development EARLY STAGE
CORPORATION