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Production Process of C4 Synthons by Biotransformation._Enzytech
Korea Health Industry Development Institute (KHIDI) South Korea flag South Korea
Abstract ID:
Production process of C3 synthons by biotransformation....
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Low Cost, High Efficiency Manufacturing Technology
A variety of techniques have been developed for the manufacturing of chiral intermediates; the classical resolution technique, biotransformation technique, and asymmetric synthesis using chiral catalyst. However technology has created trends where the use of microbial fermentation and classical resolution is gradually decreasing, while biotransformation and asymmetric synthesis utilizing chiral salen catalysts is increasing.


Currently Korean chiral drugs, as well as those offered globally, utilize chiral intermediates with high optical purity acquired through asymmetric synthesis. However this technique involves costly chiral catalysts and chiral compounds with substandard levels of optical purity.


 

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FEATURED
Last Updated Jun 2016
Technology Type PLATFORM
Phase of Development REGISTERED / FDA APPROVED / FINISHED PRODUCT
GOVERNMENT INSTITUTE