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HY209_SHAPERON Inc
Korea Health Industry Development Institute (KHIDI) South Korea flag South Korea
Abstract ID:
Sodium taurodeoxycholate for the treatment of sepsis
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Anti-inflammation (GPCR131 agonist): Based on the novel theory we suggested in 2004 on Nature Reviews Immunology, we identified a novel compound (HY209) that can ameliorate inflammatory diseases such as sepsis, collagen-induced arthritis and atopic dermatitis. It activates GPCR131 pathway inducing Myeloid-derived suppressor cells and regulatory B cells that can suppress inflammatory responses. Because HY209 increases myeloid-derived suppressor cells and regulatory B cells in vivo, the indication might be expanded to various inflammatory diseases like Alzheimer’s disease.

Type of Business Relationship Sought
<p>investment, research collaboration or technology licensing.</p>
FEATURED
Last Updated Feb 2018
Technology Type THERAPEUTIC
Phase of Development EARLY STAGE
GOVERNMENT INSTITUTE

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