Human Epidermal Growth Factor Produced in Recombinant Yeast_Gendocs
Korea Health Industry Development Institute (KHIDI) South Korea flag South Korea
Abstract ID:
Human epidermal growth factor produced in recombinant yeast
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Mechanism of Action/s (MOA):


hEGF initiate signaling cascade by binding to the EGF receptor located in the membrane. hEGF promote the growth of fibroblast which synthesize collagen, resulting in regeneration of skin and reduction of wrinkles. hEGF is registered to INCI and used as a functional ingredient for wrinkle care.


Chemistry/Characterization data:


GD-EGF(Trade name) : 53aa(exact copy of hEGF)


GD-EGFplus(Trade name) : 90aa(hEGF 53aa + fusion partner 37aa)


 In vitro bioassay data:


In vitro activity and the concentration of GD-EGF and GD-EGFplus were determined by using the commercial  ELISA kit(EGF immunoassay kit, invitrogen)


 

FEATURED
Last Updated Jun 2016
Technology Type THERAPEUTIC
Phase of Development EARLY STAGE
GOVERNMENT INSTITUTE

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