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Novel Organic Acid (MP304) Derived from Fungal Liquid Fermentation_Mycoplus Co., Ltd
Korea Health Industry Development Institute (KHIDI) South Korea flag South Korea
Abstract ID:
Novel organic acid (MP304) derived from fungal liquid fermentation...
Contact Yong U Kim
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Inhibition of cell wall synthesis

1. Summary

• The new technology is about the natural compound, MP304(Approx.190 M.W) which shows strong and broad efficacy against causal microbes of cavity, gingivitis and halitosis.

• MP304 is a member of sesquiterpenoids derived from a fungal liquid-fermentation.

• In laboratory experiment on rats, it showed little toxicity.

• Bioprocess technology for mass production has been established.

- Yield : approx. 1.5~2g/L in liquid fermentation

- very simple purification process

• MP304 is applicable to broad industrial fields including various foods & medicine.

2. Applications

• MP304 can be used as a major ingredient in tooth paste, mouth wash products, medicine, various foods and drinks to prevent or control cavity, gingivitis and halitosis.

3. Market Feasibility

• Market size for oral disease-related fields is uncountable because it can include food and pharmaceutical industries.

• The needs for natural compound specially in cavity has been constantly increasing in related industries.

4. Technical Advantages

• Most of ingredients for cavity, gingivitis and halitosis are synthetic and are not edible due to its toxicity.

• MP304 is natural with little toxicity but has broad and strong efficacy against oral pathogens. This strong advantage should satisfy customer needs.

• Productivity of natural compound from microbes is always unsatisfactory. Productivity of MP304, however, is very high yielding 1.5~2g/L thanks to strain improvement and fermentation optimization.

5. Technical Highlighted Summary

• MIC against major pathogens by alamar blue method

Type of Business Relationship Sought

Last Updated Jun 2016
Technology Type THERAPEUTIC
Phase of Development EARLY STAGE