Register or Sign in to Save this opportunity, or Send an Inquiry.
Novel Sensor of Compartment Syndrome (Ref # WFU 06-51)
Wake Forest Innovations United States flag United States
Abstract ID:
The NanoTorr™, a nanotechnology-based sensor technology, employs silver nanoparticles to provide a less-invasive, accurate, real-time measure of tissue pressure to detect and diagnose Compartment Syndrome.
Send an Inquiry

Novel Sensor of Compartment Syndrome

Value Proposition

Without rapid diagnosis, Compartment Syndrome (CS), or elevated tissue pressure in muscle, can cause irreversible muscle damage within hours. Current catheter-based methods to detect CS require multiple measurements that are invasive and prone to error. The NanoTorr overcomes these limitations and has significant potential to become the new standard method for detecting CS to prevent muscle damage.

Invention Summary

Researchers developed the NanoTorr™, a nanotechnology-based sensor that uses silver nano-particles and fiber optics to measure compartment pressure in muscle tissue. The NanoTorr rapidly and accurately measures a broad range of tissue pressures at multiple sites in real time.

Competitive Benefits

•       Unlike current methods, the NanoTorr enables healthcare providers to rapidly and easily detect CS

•       Minimally-invasive design will improve outcomes and shorten patient recovery time

•       Design will reduce manufacturing costs and increase profit margin

•       Disposable design will promote widespread use in healthcare

Application Fields

•       Emergency rooms: to rapidly detect CS resulting from vehicular crashes or blunt trauma

•       Occupational healthcare: to detect CS caused by overexertion, minimizing employee sick leave

•       Sports medicine: to detect CS caused by blunt trauma, injury or overexertion

Stage of Development

•       Prototype has been studied in a rat model


The Centers for Disease Control and Prevention reports that, annually in the United States, approximately 4 million emergency department visits can be attributed to motor vehicle accidents, 2 million to overexertion, 4 million to contusion, and 1.8 million to lower extremity injuries. A serious complication of these traumas is CS, or elevated pressure in muscle tissue. CS decreases blood supply to muscles and results in tissue death and irreversible damage.


  • David L. Carroll

  • Faith M. Coldren

  • Nicole H. Levi

  • Lawrence X. Webb

  • William D. Wagner

  • Thomas L. Smith

  • Brian Werner

  • J. Baxter Mcguirt

  • Manoj Namboothiry


Charlie Shaw, PhD

Wake Forest Innovations

Commercialization Associate

Tel:  +1.336.716.3729




Type of Business Relationship Sought
Out-license sought
Last Updated Feb 2014
Technology Type DIAGNOSTIC
Phase of Development PRECLINICAL


Opportunity Contact

Warning: include(js_message_scripts_n2.php) [function.include]: failed to open stream: No such file or directory in /home/pharmalicensing/public_html/detail.php on line 833

Warning: include() [function.include]: Failed opening 'js_message_scripts_n2.php' for inclusion (include_path='.:/usr/lib/php:/usr/local/lib/php') in /home/pharmalicensing/public_html/detail.php on line 833