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Antioxidants Rich Nutraceutical Isolated from Nigella Sativa Seed – Thymoquinone Rich Fraction (TQRF)
Putra Science Park Malaysia flag Malaysia
Abstract ID:
TQRF is a natural product with excellent nutraceutical value. It has bright yellowish oil fraction which is stable against oxidation with high level of thymoquinone. It is safe and non-toxic with light taste and aroma.
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TQRF exerts a neuroprotective role against the cytotoxic affect of AP1-40, potential as anti-nuerodegenerative agent, partly through their ability to attenuate AP-induced neurotoxicity and apoptotic features in cultures neurons. This action seems to be mediated not only by its antioxidant effect, but also by modulating intracellular signalling pathways such as caspases cascade that modulate the apoptotic process.

Since N. sativa is known to have strong antioxidant and potential chemopreventive activities, this additional benefit of anti-neurodegenerative suggests that daily consumption of N. sativa may also provide an added health benefit by reducing the risk of neurodegenerative disease such as AD.

Type of Business Relationship Sought
Licensing and Commercialisation
Last Updated Jun 2016
Technology Type THERAPEUTIC
Phase of Development EARLY STAGE

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