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8th September 2008

Welcome to this week's news update...

Licensing Opportunities
In-licensing Needs
Company Profiles
Company Releases
Industry events

EuroPLX 37 Dresden (Germany) October 6th + 7th, 2008 The Westin Bellevue Join the 37th international partnering forum for Bio/Pharma Business Development & Licensing Executives seeking deals in generics (incl. bio-generics and biosimilars), OTC drugs, and nutraceuticals: R&D, licensing, co-marketing, co-distribution, etc. EuroPLX Meetings deliver almost 24 pre-scheduled negotiations per company for delegates from more than 30 countries worldwide. A deal generating forum since 1995. See www.europlx.com
Licensing Opportunities Academic/Research H2-Caponin marker Effectively controls cell proliferation and migration more Animal health Adhesive remover available for long-term care market & veterinary market Adhesive remover available for long-term care market & veterinary market more Medical adhesive available for home care & veterinary market Medical adhesive available for home care & veterinary market more Blood and forming organs Therapeutic factors for stabilizing blood vessels and preventing hemorrhage, and promoting angiogenesis following ischemia A novel combination of growth factors that may serve as a basis for promoting blood vessel formation, and stabilizing those vessels whose stability may be compromised more Cardiovascular A battery of genetic biomarkers of severe outcome in patients with elevated triglyceride levels A renowned cardiologist and Robarts' Scientist has identified a strong correlation between a polymorphism of a relatively new apolipoprotein gene and severity of hypertiglyceridemia manifestation more CIP - Fenofibrate CIP-Fenofibrate is a novel oral formulation of Fenofibrate capsules that has been developed using new proprietary, superbioavailable drug delivery technology referred to as Lidose® more Troponin test for AMI Submolecular markers that leverages the earliest diagnostic test of acute myocardial infarction more Central Nervous System Buprenorphine 0.4 - 2 - 8 mg sublingual tablets Substitution treatment for opiod drug addiction more CIP - Tramadol ER The novel formulation means that CIP-Tramadol ER delivers 24 hour sustained release, with once-daily dosing, supporting ease-of-use for physicians, and a high level of compliance among chronic pain sufferers more Sulidin® nimesulide LPS non-steroidal topical anti-inflammatory gel for the local treatment of painful inflammatory conditions Using a lamellar structure as a delivery system, the Sulidin® Nimesulide LPS gel provides enhanced percutaneous penetration of Nimesulide and reduced yellow staining on the skin. LPS Technology worldwide patents are pending more Topical anesthetic for long-term care market Topical anesthetic for long-term care market more Dermatological CIP - Isotretinoin CIP-Isotretinoin is a novel oral formulation of Isotretinoin that has been developed using the proprietary Lidose® technology more Control of acne causing organisms in a topical cream/gel Antimicrobial polymer for use as a topical treatment for acne more Kortos® Cream and Kortos® HC cream for the treatment of acute hemorrhoids, anal fissure and anal pruritus Kortos® Cream contains anti-inflammatory-antipruritic-vasoconstrictor, astringent, antiseptic and local anesthetic in a special water repellant base more Novel dual chamber dispenser for Rx and OTC dermatology products Novel dual chamber dispenser with polycarbonate and stainless steel components for accurate Rx dosing more Potent and safe anti-itch product Non-steroidal OTC or potential Rx anti-itch product more Rx and OTC acne/rosacea medications Rx and OTC acne medications more Topical compound inhibits nociceptive pain and TNF-alpha secretion Our patented technology, when applied topically, inhibits nociceptive pain and neurogenic inflammation that occurs from the secretion of TNF-alpha, IL-1alpha and IL-6 more Diagnostic Blood diagnostic marker for Alzheimer's disease The measurement of GSK-3 in circulating white cells is a useful early diagnostic marker and potential therapy for Alzheimer's disease more High resolution full-body MR angiography series Whole-body Magnetic Resonance Angiography (MRA) software/system enhancement techniques that provide rapid, high resolution, 3D, imaging capabilities more MRI Coil Novel Slab-Selective MRI Coil for maximal diagnostic effectiveness more Drug delivery Coated bead system Multiparticles for oral formulations, based on coating technology with fluid bed or perforated coating pan more Fast dispersible tablets For rapid dispersion in mouth or glass of water more Liquid crystalline nanoparticles (LCNP) Liquid crystalline nanoparticles, comprising cubic, hexagonal or sponge inner phases, for oral, topical or iv delivery more Matrix tablets (hydro- and lipo-inert) For oral formulations; particles are coated more SoluleavesTM - Melt in the mouth film strips We are seeking to out-license our innovative Soluleaves range more Technology for sc/im sustained release injectables of peptides, proteins and small molecules Non-aqueous, low-viscous, injectable liquid, forming a liquid crystalline (LC) depot in the sc/im tissue, from which the drug is slowly released more XGEL (TM) polymer technology The XGEL ™ polymer technology is available for licensing and replaces the need to use animal-derived gelatine in pharmaceutical and healthcare products more Drug discovery Cytochrome P450 license programme Crystal structures of human cytochrome P450s and their uses in drug discovery more Gastrointestinal Ondansetron OroDispersible tablets 4-8 mg Generic dossier more Genetic disorders Ditag genome scanning technology Novel gene scanning methodology more Genito-urinary Low dose Estradiol/Progestin tablets Low dose Estradiol / Progestin combination product for treatment of menopausal disorders. more Neo-Penotran® topical broad spectrum anti-infective vaginal pessary and cream for the treatment of three main types of vaginal infections and mixed forms of vaginitis Each Dose of Neo-Penotran® contains a combination of Metronidazole and Miconazole Nitrate in therapeutic concentrations for the local treatment of the treatment three main types of vaginal infections and mixed forms of vaginitis more Hospital and Surgery Surgical instrument Surgical instrument for tissue resection and ureteral dissection more Immune related disorders CASAC: A Th1 adjuvant Adjuvant that induces a potent antigen-specific CD8 cytotoxic T-cell response with long lasting immunity more p38 MAP kinase inhibitors for treatment of inflammation-related disorders p38 MAP Kinase inhibitors as modulators of pro-inflammatory cytokine-expression for treatment of inflammation-related diseases like rheumatoid arthritis, inflammatory bowel disease, psoriasis, or acute coronary syndrome more Infectious diseases Control of impetigo caused by Streptococcus and Staphylococcus Unique class-leading technology offering a safe and effective alternative to antibiotics and conventional antimicrobials more Control of multi-resistant bacteria (MRSA, VRE and ESBL) in a topical application Chemeq Technologies' patented polymeric antimicrobial technology targets the control of microbes in a range of markets more Medical device Cellophil(TM) Biomedical polymer - New and superior biomedical polymers for a new standard in the medical device industry. Cellophil (TM) is particularly designed for optical lenses, drug delivery and also may be used as additive for food and cosmetics or as fiber for fabrics more Musculoskeletal High Precision Radiostereometric Analysis (RSA) System for monitoring micro-movement in orthopedic implants A new universal RSA calibration system that eliminates the need for joint-specific calibration boxes and analysis. 40% to 70% more accurate than existing technologies more Oncology Coformycin Novel cancer therapy for epithelial cancers more NLCQ-1 Novel cancer therapy for optimizing therapeutic efficacy more Oncolytic adenovirus Novel cancer therapy that simultaneously treats primary & metastatic tumors more Pharmaceutical OTC and ethical products (Dexo US, Dexo France) We are seeking to out-license our product portfolio to territories where we do not have sales and marketing operations more
In-licensing Needs Dermatological Topical wound care treatments for burns, trauma & diabetic wounds Topical wound care treatments for burns, trauma & diabetic wounds more Genito-urinary Intimate hygiene products, technologies and packaging Products, technologies and packaging that offer improved performance in the area of intimate hygiene more OTC consumer diagnostic kits relevant to sexual well being In licensing needs: Seeking opportunities for OTC consumer diagnostic kits relevant to sexual well-being more OTC personal and sexual lubricants In licensing needs: Seeking opportunities for OTC consumer products used for personal and sexual lubrication more OTC sexual enhancement consumer products Seeking device opportunities for OTC consumer products that deliver sexual enhancement more Infectious disease Topical infection control – including surgery preps, scrubs and sealants Topical infection control more Company profiles Decision Resources The worldwide leader in market research publications, advisory services and consulting DESMA PHARMA Group DESMA PHARMA Group manufactures and markets proprietary, branded, ethical and OTC products in more than 40 countries worldwide King's College London Business King's College London Business Ltd is responsible for commercialisation of technologies emanating from King's. Opportunities include: Collaborative & contract research, consultancy and clinical trials Navamedic Navamedic is a Scandinavian specialty pharma company focusing on registration and marketing. Therapeutic areas include OA, medical nutrition, oral medicine, female care, addictions and dermatology Pharmalicensing pharmalicensing.com - Open Innovation for the life sciences Company Releases Physicians eager to increase their first- and second-line prescriptions for Januvia over the next two years for the treatment of type 2 diabetes PPAR-Gamma Agonists share of second-line treatment is declining, according to a new report from Decision Resources Decision Resources, inc. launches new web site Company's growth attributed to nurturing brand companies Vaccine technology breakthrough at King's Dr Alistair Noble from the MRC & Asthma UK Centre in Allergic Mechanisms of Asthma at King's, has developed a new technology for vaccine development which could be used for a variety of diseases such as asthma, Tuberculosis, HIV and influenza China's hepatitis B virus drug market will grow to $800 million by 2012 Competition from Chinese makers present considerable challenge to branded western drug companies seeking to penetrate market, according to a new report from decision resources Florida is state with highest percentage of untreated patients with chronic obstructive pulmonary disease Utah and Mississippi rank very low in treatment rate for asthma and chronic obstructive pulmonary disease, according to a new analytics tool from Decision Resources Half of surveyed physicians expect to replace between 6 percent and 15 percent of their Sustiva prescriptions with Isentress Most surveyed MCO pharmacy directors do not place cost control measures on branded antiretroviral drugs, according to a new report from Decision Resources New hope for heart failure patients New hope for heart failure patients Lawson scientist awarded Heart & Stroke Foundation grant for patient portal project Researchers will study the benefit of innovative online education and monitoring tools developed by Lawson and MedManager for heart failure patients Events
BioNetwork West 6 -8 Oct 2008 — The Ritz-Carlton Laguna Niguel, CA , USA Partnerships are vital to your company's success. Complementary resources - biotech's innovative products and pharma's deep pockets - have been the impetus for many strategic alliances. Yet the cold truth is that most of them fail. How will you avoid a similar fate with your next partner? BioNetwork 2008 will provide the knowledge you need to drive business success Event detail Email event organizer	2008 Leaders' Forum: Two parallel conferences 28 -30 Oct 2008 — San Diego, USA Two sector-leading meetings co-located for the first time - the thirteenth Phacilitate R&D Leaders' Forum and the third Phacilitate Oncology Leaders' Forum. You will be able to attend sessions during both programs and enjoy superb networking opportunities in the shared exhibition area Event details Email event organizer

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